aciclovir

aciclovir

Clinical data
Pronunciation	/eɪˈsaɪkloʊvɪər/
Trade names	Zovirax, others
Other names	Acycloguanosine, acyclovir (BAN UK), acyclovir (USAN US)
AHFS/Drugs.com	Acyclovir Monograph Acyclovir topical Monograph
MedlinePlus	a681045
License data	US DailyMed: Acyclovir
Pregnancy category	AU: B3
Routes of administration	Intravenous, by mouth, topical, eye ointment
ATC code	J05AB01 (WHO) D06BB03 (WHO), S01AD03 (WHO), D06BB53 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) CA: ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability	15–20% (by mouth)
Protein binding	9–33%
Metabolism	Liver
Elimination half-life	2–4 hours
Excretion	Kidney (62–90% as unchanged drug)
Identifiers
IUPAC name 2-amino-1,9-dihydro-9-((2-hydroxyethoxy)methyl)-3H-purin-6-one
CAS Number	59277-89-3
PubChem CID	2022
PubChem SID	46506002
IUPHAR/BPS	4829
DrugBank	DB00787
ChemSpider	1945
UNII	X4HES1O11F
KEGG	D00222 C06810
ChEBI	CHEBI:2453
ChEMBL	ChEMBL184
PDB ligand	AC2 (PDBe, RCSB PDB)
Chemical and physical data
Formula	C8H11N5O3
Molar mass	225.208 g·mol−1
3D model (JSmol)	Interactive image
Melting point	256.5 °C (493.7 °F)
SMILES O=C2/N=C(\Nc1n(cnc12)COCCO)N
InChI InChI=1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15) Key:MKUXAQIIEYXACX-UHFFFAOYSA-N
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Angol

Főnév

aciclovir (tsz. aciclovirs)

1. (gyógyszertan) aciklovir

További információk

• aciclovir - Szótár.net (en-hu)
• aciclovir - Sztaki (en-hu)
• aciclovir - Merriam–Webster
• aciclovir - Cambridge
• aciclovir - WordNet
• aciclovir - Яндекс (en-ru)
• aciclovir - Google (en-hu)
• aciclovir - Wikidata
• aciclovir - Wikipédia (angol)