baclofen

baclofen

Clinical data
Trade names	Lioresal, others
Other names	β-(4-chlorophenyl)-γ-aminobutyric acid (β-(4-chlorophenyl)-GABA)
AHFS/Drugs.com	Monograph
MedlinePlus	a682530
License data	US DailyMed: Baclofen
Pregnancy category	AU: B3
Routes of administration	oral, intrathecal, transdermal
ATC code	M03BX01 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) CA: ℞-only NZ: Prescription only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability	Well-absorbed
Protein binding	30%
Metabolism	85% excreted in urine/faeces unchanged. 15% metabolised by deamination
Elimination half-life	2.5 to 7 hours
Excretion	Kidney (70–80%)
Identifiers
IUPAC name (RS)-4-Amino-3-(4-chlorophenyl)butanoic acid
CAS Number	1134-47-0 Y
PubChem CID	2284
IUPHAR/BPS	1084
DrugBank	DB00181 Y
ChemSpider	2197 Y
UNII	H789N3FKE8
KEGG	D00241 Y
ChEBI	CHEBI:2972 Y
ChEMBL	ChEMBL701 Y
Chemical and physical data
Formula	C10H12ClNO2
Molar mass	213.661 g·mol−1
3D model (JSmol)	Interactive image
Chirality	Racemic mixture
SMILES NCC(CC(=O)O)c1ccc(Cl)cc1
InChI InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14) Y Key:KPYSYYIEGFHWSV-UHFFFAOYSA-N Y
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Angol

Főnév

baclofen (tsz. baclofens)

1. (gyógyszertan) baklofén

További információk

• baclofen - Szótár.net (en-hu)
• baclofen - Sztaki (en-hu)
• baclofen - Merriam–Webster
• baclofen - Cambridge
• baclofen - WordNet
• baclofen - Яндекс (en-ru)
• baclofen - Google (en-hu)
• baclofen - Wikidata
• baclofen - Wikipédia (angol)