citalopram

citalopram

(R)-(−)-citalopram (top), (S)-(+)-citalopram (bottom)
Clinical data
Pronunciation	/saɪˈtæləˌpræm, sɪ-/ sy-TA-lə-pram
Trade names	Celexa, Cipramil, others
AHFS/Drugs.com	Monograph
MedlinePlus	a699001
License data	US DailyMed: Citalopram
Pregnancy category	AU: C
Dependence liability	Low
Addiction liability	Low
Routes of administration	oral, intravenous
Drug class	Selective serotonin reuptake inhibitor (SSRI)
ATC code	N06AB04 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) BR: Class C1 (Other controlled substances) CA: ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability	80% peak at 4 hours
Protein binding	<80%
Metabolism	Liver (CYP3A4 and CYP2C19)
Metabolites	Desmethylcitalopram (DCT) and didesmethylcitalopram (DDCT)
Elimination half-life	35 hours
Excretion	Mostly as unmetabolized citalopram, partly DCT, and traces of DDCT in urine
Identifiers
IUPAC name (RS)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile
CAS Number	59729-33-8 Y
PubChem CID	2771
IUPHAR/BPS	7547
DrugBank	DB00215 Y
ChemSpider	2669 Y
UNII	0DHU5B8D6V
KEGG	D07704 Y as salt: D00822 Y
ChEBI	CHEBI:3723 Y
ChEMBL	ChEMBL549 Y
Chemical and physical data
Formula	C20H21FN2O
Molar mass	324.399403163 g·mol−1
3D model (JSmol)	Interactive image
Chirality	Racemic mixture
SMILES Fc1ccc(cc1)C3(OCc2cc(C#N)ccc23)CCCN(C)C
InChI InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3 Y Key:WSEQXVZVJXJVFP-UHFFFAOYSA-N Y
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Angol

Főnév

citalopram (tsz. citaloprams)

1. (gyógyszertan) citaloprám

További információk

• citalopram - Szótár.net (en-hu)
• citalopram - Sztaki (en-hu)
• citalopram - Merriam–Webster
• citalopram - Cambridge
• citalopram - WordNet
• citalopram - Яндекс (en-ru)
• citalopram - Google (en-hu)
• citalopram - Wikidata
• citalopram - Wikipédia (angol)