doxycycline

doxycycline

Clinical data
Pronunciation	/ˌdɒksɪˈsaɪkliːn/ DOK-see-SEYE-kleen
Trade names	Vibramycin, others
AHFS/Drugs.com	Monograph
MedlinePlus	a682063
License data	US DailyMed: Doxycycline
Pregnancy category	AU: D
Routes of administration	By mouth, intravenous
ATC code	J01AA02 (WHO) A01AB22 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability	~100%
Protein binding	80–90%
Metabolism	Negligible
Elimination half-life	10–22 hours
Excretion	Mainly feces, 40% urine
Identifiers
IUPAC name (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
CAS Number	564-25-0
PubChem CID	Doxycycline
DrugBank	DB00254
ChemSpider	10482106
UNII	334895S862
KEGG	D07876
ChEBI	CHEBI:60648
ChEMBL	ChEMBL1433
Chemical and physical data
Formula	C22H24N2O8
Molar mass	444.44 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN(C)[C@@H]3C(\O)=C(\C(N)=O)C(=O)[C@@]4(O)C(/O)=C2/C(=O)c1c(cccc1O)[C@H](C)[C@H]2[C@H](O)[C@@H]34
InChI InChI=1S/C22H24N2O8.H2O/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31);1H2/t7-,10+,14+,15-,17-,22-;/m0./s1 Key:XQTWDDCIUJNLTR-CVHRZJFOSA-N

Angol

Főnév

doxycycline (tsz. doxycyclines)

1. (gyógyszertan) doxiciklin

További információk

• doxycycline - Szótár.net (en-hu)
• doxycycline - Sztaki (en-hu)
• doxycycline - Merriam–Webster
• doxycycline - Cambridge
• doxycycline - WordNet
• doxycycline - Яндекс (en-ru)
• doxycycline - Google (en-hu)
• doxycycline - Wikidata
• doxycycline - Wikipédia (angol)