escitalopram

escitalopram

Clinical data
Pronunciation	/ˌɛsəˈtæləˌpræm/
Trade names	Cipralex, Lexapro, others
Other names	(S)-Citalopram; S-Citalopram; S-(+)-Citalopram; S(+)-Citalopram; (+)-Citalopram; LU-26054; MLD-55
AHFS/Drugs.com	Monograph
MedlinePlus	a603005
License data	US DailyMed: Escitalopram
Pregnancy category	AU: C
Routes of administration	By mouth
Drug class	Selective serotonin reuptake inhibitor (SSRI)
ATC code	N06AB10 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) BR: Class C1 (Other controlled substances) CA: ℞-only UK: POM (Prescription only) US: ℞-only EU: Rx-only In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability	~80%
Protein binding	~55–56% (low)
Metabolism	Liver (CYP2C19, CYP3A4, CYP2D6)
Metabolites	• Desmethylcitalopram • Didesmethylcitalopram
Elimination half-life	~27–32 hours
Excretion	Urine (major; 8–10% unchanged), feces (minor)
Identifiers
IUPAC name (S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile
CAS Number	128196-01-0 Y
PubChem CID	146570
DrugBank	DB01175 Y
ChemSpider	129277 Y
UNII	4O4S742ANY
KEGG	D07913
ChEBI	CHEBI:36791 Y
ChEMBL	ChEMBL1508 Y
Chemical and physical data
Formula	C20H21FN2O
Molar mass	324.399403163 g·mol−1
3D model (JSmol)	Interactive image
Chirality	Levorotatory enantiomer
SMILES Fc1ccc(cc1)[C@@]3(OCc2cc(C#N)ccc23)CCCN(C)C
InChI InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3/t20-/m0/s1 Y Key:WSEQXVZVJXJVFP-FQEVSTJZSA-N Y
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Angol

Főnév

escitalopram (tsz. escitaloprams)

1. (gyógyszertan) eszcitaloprám

További információk

• escitalopram - Szótár.net (en-hu)
• escitalopram - Sztaki (en-hu)
• escitalopram - Merriam–Webster
• escitalopram - Cambridge
• escitalopram - WordNet
• escitalopram - Яндекс (en-ru)
• escitalopram - Google (en-hu)
• escitalopram - Wikidata
• escitalopram - Wikipédia (angol)