irbesartan

irbesartan

Clinical data
Pronunciation	/ɜːrbəˈsɑːrtən/
Trade names	Aprovel, Avapro, others
AHFS/Drugs.com	Monograph
MedlinePlus	a698009
License data	US DailyMed: Irbesartan
Pregnancy category	AU: D
Routes of administration	By mouth
Drug class	Cardiovascular agent
ATC code	C09CA04 (WHO) C09DA04 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only EU: Rx-only In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability	60% to 80%
Protein binding	~90%
Metabolism	Liver (CYP2C9)
Elimination half-life	11 h to 15 h
Excretion	Kidney 20%, feces 65%
Identifiers
IUPAC name 2-butyl-3-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1,3-diazaspiro[4.4]non-1-en-4-one
CAS Number	138402-11-6 Y
PubChem CID	3749
IUPHAR/BPS	589
DrugBank	DB01029 Y
ChemSpider	3618 Y
UNII	J0E2756Z7N
KEGG	D00523 Y
ChEBI	CHEBI:5959 Y
ChEMBL	ChEMBL1513 Y
Chemical and physical data
Formula	C25H28N6O
Molar mass	428.54 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C1N(\C(=N/C12CCCC2)CCCC)Cc5ccc(c3ccccc3c4n[nH]nn4)cc5
InChI InChI=1S/C25H28N6O/c1-2-3-10-22-26-25(15-6-7-16-25)24(32)31(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23-27-29-30-28-23/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,27,28,29,30) Y Key:YOSHYTLCDANDAN-UHFFFAOYSA-N Y
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Angol

Főnév

irbesartan (tsz. irbesartans)

1. (gyógyszertan) irbezartán

További információk

• irbesartan - Szótár.net (en-hu)
• irbesartan - Sztaki (en-hu)
• irbesartan - Merriam–Webster
• irbesartan - Cambridge
• irbesartan - WordNet
• irbesartan - Яндекс (en-ru)
• irbesartan - Google (en-hu)
• irbesartan - Wikidata
• irbesartan - Wikipédia (angol)