mirtazapine

mirtazapine

Clinical data
Trade names	Remeron, others
Other names	Mepirzapine; 6-Azamianserin; ORG-3770
AHFS/Drugs.com	Monograph
MedlinePlus	a697009
License data	US DailyMed: Mirtazapine
Pregnancy category	AU: B3
Routes of administration	By mouth, topical
Drug class	Noradrenergic and specific serotonergic antidepressant (NaSSA)
ATC code	N06AX11 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) BR: Class C1 (Other controlled substances) CA: ℞-only UK: POM (Prescription only) US: ℞-only EU: Rx-only
Pharmacokinetic data
Bioavailability	50%
Protein binding	85%
Metabolism	Liver (CYP1A2, CYP2D6, CYP3A4)
Metabolites	Desmethylmirtazapine (contributes 3–10% of activity)
Elimination half-life	20–40 hours
Excretion	Urine: 75% Feces: 15%
Identifiers
IUPAC name (±)-5-methyl-2,5,19-triazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(15),8,10,12,16,18-hexaene
CAS Number	85650-52-8 Y
PubChem CID	4205
IUPHAR/BPS	7241
DrugBank	DB00370 Y
ChemSpider	4060 Y
UNII	A051Q2099Q
KEGG	D00563 Y
ChEBI	CHEBI:6950 Y
ChEMBL	ChEMBL654 Y
Chemical and physical data
Formula	C17H19N3
Molar mass	265.36 g·mol−1
3D model (JSmol)	Interactive image
Chirality	Racemic mixture
Density	1.22 g/cm3
Melting point	114 to 116 °C (237 to 241 °F)
Boiling point	432 °C (810 °F)
Solubility in water	Soluble in methanol and chloroform mg/mL (20 °C)
SMILES n1cccc3c1N4C(c2ccccc2C3)CN(C)CC4
InChI InChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3 Y Key:RONZAEMNMFQXRA-UHFFFAOYSA-N Y
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Főnév

mirtazapine (tsz. mirtazapines)

1. (gyógyszertan) mirtazapin

További információk

• mirtazapine - Szótár.net (en-hu)
• mirtazapine - Sztaki (en-hu)
• mirtazapine - Merriam–Webster
• mirtazapine - Cambridge
• mirtazapine - WordNet
• mirtazapine - Яндекс (en-ru)
• mirtazapine - Google (en-hu)
• mirtazapine - Wikidata
• mirtazapine - Wikipédia (angol)