amantadine

amantadine

Clinical data
Trade names	Gocovri, Symadine, Symmetrel, others
Other names	1-Adamantylamine; 1-Adamantanamine; 1-Aminoadamantane; Midantane; Midantan
AHFS/Drugs.com	Monograph
MedlinePlus	a682064
License data	US DailyMed: Amantadine
Pregnancy category	AU: B3
Routes of administration	By mouth
ATC code	N04BB01 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) BR: Class C1 (Other controlled substances) CA: ℞-only UK: POM (Prescription only) US: ℞-only CN: OTC
Pharmacokinetic data
Bioavailability	86–90%
Protein binding	67%
Metabolism	Minimal (mostly to acetyl metabolites)
Elimination half-life	10–31 hours
Excretion	Urine
Identifiers
IUPAC name Adamantan-1-amine
CAS Number	768-94-5 Y as HCl: 665-66-7
PubChem CID	2130 as HCl: 64150
IUPHAR/BPS	4128
DrugBank	DB00915 Y as HCl: DBSALT000203
ChemSpider	2045 Y as HCl: 57724
UNII	BF4C9Z1J53 as HCl: M6Q1EO9TD0
KEGG	D07441 Y as HCl: D00777 Y
ChEBI	CHEBI:2618 Y as HCl: CHEBI:2619
ChEMBL	ChEMBL660 Y as HCl: ChEMBL1569
Chemical and physical data
Formula	C10H17N
Molar mass	151.253 g·mol−1
3D model (JSmol)	Interactive image
Melting point	180 °C (356 °F)
SMILES C1C2CC3CC1CC(C2)(C3)N
InChI InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2 Y Key:DKNWSYNQZKUICI-UHFFFAOYSA-N Y
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Angol

Főnév

amantadine (tsz. amantadines)

1. (gyógyszertan) amantadin

További információk

• amantadine - Szótár.net (en-hu)
• amantadine - Sztaki (en-hu)
• amantadine - Merriam–Webster
• amantadine - Cambridge
• amantadine - WordNet
• amantadine - Яндекс (en-ru)
• amantadine - Google (en-hu)
• amantadine - Wikidata
• amantadine - Wikipédia (angol)