brexpiprazole

brexpiprazole

Clinical data
Pronunciation	/brɛkˈspɪprəzoʊl/ brek-SPIP-rə-zohl
Trade names	Rexulti, Rxulti, others
Other names	OPC-34712
AHFS/Drugs.com	Monograph
MedlinePlus	a615046
License data	US DailyMed: Brexpiprazole
Pregnancy category	AU: C
Routes of administration	By mouth
Drug class	Atypical antipsychotic
ATC code	N05AX16 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) BR: Class C1 (Other controlled substances) CA: ℞-only US: ℞-only EU: Rx-only In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability	95% (Tmax = 4 hours)
Protein binding	>99%
Metabolism	Liver (mainly mediated by CYP3A4 and CYP2D6)
Elimination half-life	91 hours (brexpiprazole), 86 hours (major metabolite)
Excretion	Feces (46%), urine (25%)
Identifiers
IUPAC name 7-[4-[4-(1-benzothiophen-4-yl)piperazin-1-yl]butoxy]quinolin-2(1H)-one
CAS Number	913611-97-9
PubChem CID	11978813
DrugBank	DB09128
ChemSpider	10152155
UNII	2J3YBM1K8C
KEGG	D10309
ChEBI	CHEBI:134716
ChEMBL	ChEMBL2105760
Chemical and physical data
Formula	C25H27N3O2S
Molar mass	433.57 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C5/C=C\c4ccc(OCCCCN3CCN(c1cccc2sccc12)CC3)cc4N5
InChI InChI=1S/C25H27N3O2S/c29-25-9-7-19-6-8-20(18-22(19)26-25)30-16-2-1-11-27-12-14-28(15-13-27)23-4-3-5-24-21(23)10-17-31-24/h3-10,17-18H,1-2,11-16H2,(H,26,29) Key:ZKIAIYBUSXZPLP-UHFFFAOYSA-N

Angol

Főnév

brexpiprazole (tsz. brexpiprazoles)

1. (gyógyszertan) brexpiprazol

További információk

• brexpiprazole - Szótár.net (en-hu)
• brexpiprazole - Sztaki (en-hu)
• brexpiprazole - Merriam–Webster
• brexpiprazole - Cambridge
• brexpiprazole - WordNet
• brexpiprazole - Яндекс (en-ru)
• brexpiprazole - Google (en-hu)
• brexpiprazole - Wikidata
• brexpiprazole - Wikipédia (angol)