cariprazine

cariprazine

Clinical data
Pronunciation	/kəˈrɪprəˌziːn/
Trade names	Vraylar, Reagila, Symvenu
Other names	RGH-188
AHFS/Drugs.com	Monograph
License data	US DailyMed: Cariprazine US FDA: Cariprazine
Pregnancy category	AU: D
Routes of administration	By mouth
Drug class	Atypical antipsychotic
ATC code	N05AX15 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) CA: ℞-only UK: POM (Prescription only) US: ℞-only EU: Rx-only
Pharmacokinetic data
Bioavailability	High
Protein binding	91–97%
Metabolism	Liver via CYP3A4 and to a lesser extent CYP2D6
Metabolites	desmethylcariprazine, didesmethylcariprazine
Elimination half-life	2–4 days for parent drug, and 1–3 weeks for active metabolites
Excretion	Urine (21%), bile
Identifiers
IUPAC name N'-[trans-4-[2-[4-(2,3-Dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-N,N-dimethylurea
CAS Number	839712-12-8
PubChem CID	11154555
IUPHAR/BPS	7671
DrugBank	DB06016
ChemSpider	25999972
UNII	F6RJL8B278
KEGG	D09997 as HCl: D09876
ChEBI	CHEBI:90933
ChEMBL	ChEMBL2028019
Chemical and physical data
Formula	C21H32Cl2N4O
Molar mass	427.414 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1
InChI InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23/h3-5,16-17H,6-15H2,1-2H3,(H,24,28)/t16-,17- Y Key:KPWSJANDNDDRMB-QAQDUYKDSA-N Y

Angol

Főnév

cariprazine (tsz. cariprazines)

1. (gyógyszertan) kariprazin

További információk

• cariprazine - Szótár.net (en-hu)
• cariprazine - Sztaki (en-hu)
• cariprazine - Merriam–Webster
• cariprazine - Cambridge
• cariprazine - WordNet
• cariprazine - Яндекс (en-ru)
• cariprazine - Google (en-hu)
• cariprazine - Wikidata
• cariprazine - Wikipédia (angol)