ceftaroline

ceftaroline
Clinical data
Trade names	Teflaro, Zinforo
Other names	PPI 0903, TAK-599
AHFS/Drugs.com	Monograph
MedlinePlus	a611014
License data	EU EMA: by INN; US DailyMed: Ceftaroline_fosamil; US FDA: Ceftaroline;
Pregnancy; category	AU: B1;
Routes of; administration	Intravenous
ATC code	J01DI02 (WHO) ;
Legal status
Legal status	AU: S4 (Prescription only); US: ℞-only; EU: Rx-only;
Pharmacokinetic data
Protein binding	20%
Elimination half-life	2.5 hours
Excretion	Urine (88%), faeces (6%)
Identifiers
	IUPAC name (6R,7R)-7-[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-3-[4-(1-methylpyridin-1-ium-4-yl)-1,3-thiazol-2-yl]sulfanyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;
CAS Number	229016-73-3 ; anhydrous: 400827-46-5 ;
PubChem CID	16007393; anhydrous: 9852981;
DrugBank	DB06590 ;
ChemSpider	8028692 ;
UNII	7P6FQA5D21; anhydrous: EZ9W6O5S09 ;
KEGG	D08884;
ChEBI	CHEBI:70718 ;
ChEMBL	ChEMBL501122 ;
Chemical and physical data
Formula	C22H21N8O8PS4
Molar mass	684.671761998 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C4N3/C(=C(/Sc2nc(c1cc[n+](cc1)C)cs2)CS[C@@H]3[C@@H]4NC(=O)C(=N\OCC)/c5nc(sn5)NP(=O)(O)O)C([O-])=O;
	InChI InChI=1S/C22H21N8O8PS4/c1-3-38-26-13(16-25-21(43-28-16)27-39(35,36)37)17(31)24-14-18(32)30-15(20(33)34)12(9-40-19(14)30)42-22-23-11(8-41-22)10-4-6-29(2)7-5-10/h4-8,14,19H,3,9H2,1-2H3,(H4-,24,25,27,28,31,33,34,35,36,37)/b26-13-/t14-,19-/m1/s1 ; Key:ZCCUWMICIWSJIX-NQJJCJBVSA-N ;
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Angol

ceftaroline (tsz. ceftarolines)

↑ Forráshivatkozás-hiba: Érvénytelen <ref> címke; nincs megadva szöveg a(z) Teflaro FDA label nevű lábjegyzeteknek
↑ Forráshivatkozás-hiba: Érvénytelen <ref> címke; nincs megadva szöveg a(z) Zinforo EPAR nevű lábjegyzeteknek