ceftobiprole

ceftobiprole
Clinical data
Trade names	Zevtera, Mabelio
Other names	RO0639141-000, BAL9141, ceftobiprole medocaril
AHFS/Drugs.com	Zevtera
License data	US DailyMed: Ceftobiprole;
Routes of; administration	Intravenous
Drug class	Cephalosporin antibacterial
ATC code	J01DI01 (WHO) ;
Legal status
Legal status	AU: S4 (Prescription only); CA: ℞-only; UK: POM (Prescription only); US: ℞-only; In general: ℞ (Prescription only);
Identifiers
	IUPAC name (6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-ylidene)- 2-nitroso-1-oxoethyl]amino]-8-oxo-3-[(E)-[2-oxo-1-[(3R)- 3-pyrrolidinyl]-3-pyrrolidinylidene]methyl]-5-thia-1- azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;
CAS Number	209467-52-7 ; as medocaril: 252188-71-9;
PubChem CID	6918430; as medocaril: 135413543;
DrugBank	DB04918 ; as medocaril: DB14733;
ChemSpider	23350302 ; as medocaril: 30791463;
UNII	5T97333YZK; as medocaril: N99027V28J;
KEGG	D08885 ; as medocaril: D08886;
ChEMBL	ChEMBL520642 ;
Chemical and physical data
Formula	C20H22N8O6S2
Molar mass	534.566 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1CNC[C@@H]1N2CC/C(=C\C3=C(N4[C@@H]([C@@H](C4=O)NC(=O)/C(=N\O)/c5nc(sn5)N)SC3)C(=O)O)/C2=O;
	InChI InChI=1S/C20H22N8O6S2/c21-20-24-14(26-36-20)11(25-34)15(29)23-12-17(31)28-13(19(32)33)9(7-35-18(12)28)5-8-2-4-27(16(8)30)10-1-3-22-6-10/h5,10,12,18,22,34H,1-4,6-7H2,(H,23,29)(H,32,33)(H2,21,24,26)/b8-5+,25-11-/t10-,12-,18-/m1/s1 ; Key:VOAZJEPQLGBXGO-SDAWRPRTSA-N ;
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Angol

ceftobiprole (tsz. ceftobiproles)

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↑ Prescription medicines: registration of new chemical entities in Australia, 2015. Therapeutic Goods Administration (TGA) , 2022. június 21. [2023. április 10-i dátummal az eredetiből archiválva].
↑ Zevtera Product information. Health Canada , 2010. április 23. [2024. február 19-i dátummal az eredetiből archiválva].
↑ Zevtera Product information. Health Canada , 2018. március 20. [2024. április 30-i dátummal az eredetiből archiválva].
↑ Zevtera- ceftobiprole medocaril sodium injection, powder, for solution. DailyMed , 2025. március 21.