clavulanate

clavulanate

Clinical data
Pronunciation	ˌklævjʊˈlænᵻk
Other names	RX-10100; Serdaxin; Zoraxel
AHFS/Drugs.com	clavulanic-acid
Pregnancy category	AU: B1
Routes of administration	Oral, IV
ATC code	J01CR (WHO) (combinations with penicillins)
Legal status
Legal status	AU: S4 (Prescription only) In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability	Oral: 45–64%
Protein binding	~25%
Metabolism	Unknown
Metabolites	Two minor metabolites
Onset of action	≤0.67–2 hours (TmaxTooltip time to peak concentrations)
Elimination half-life	0.8–1.2 hours
Excretion	Urine: 35–65% (unchanged; within 6 hours)
Identifiers
IUPAC name (2R,5R,Z)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid
CAS Number	58001-44-8
PubChem CID	5280980
DrugBank	DB00766
ChemSpider	4444466
UNII	23521W1S24
KEGG	D07711
ChEBI	CHEBI:48947
ChEMBL	ChEMBL777
Chemical and physical data
Formula	C8H9NO5
Molar mass	199.162 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C2N1[C@H](C(/O[C@@H]1C2)=C/CO)C(=O)O
InChI InChI=1S/C8H9NO5/c10-2-1-4-7(8(12)13)9-5(11)3-6(9)14-4/h1,6-7,10H,2-3H2,(H,12,13)/b4-1-/t6-,7-/m1/s1 Key:HZZVJAQRINQKSD-PBFISZAISA-N
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Angol

Főnév

clavulanate (tsz. clavulanates)

1. (gyógyszertan) klavulánsav

További információk

• clavulanate - Szótár.net (en-hu)
• clavulanate - Sztaki (en-hu)
• clavulanate - Merriam–Webster
• clavulanate - Cambridge
• clavulanate - WordNet
• clavulanate - Яндекс (en-ru)
• clavulanate - Google (en-hu)
• clavulanate - Wikidata
• clavulanate - Wikipédia (angol)