colistin

colistin

Clinical data
Trade names	Xylistin, Coly-Mycin M, Colobreathe, others
AHFS/Drugs.com	Monograph
MedlinePlus	a682860
License data	US DailyMed: Colistimethate
Routes of administration	Topical, by mouth, intravenous, intramuscular, inhalation
ATC code	A07AA10 (WHO) J01XB01 (WHO), QA07AA10 (WHO), QA07AA98 (WHO), QG51AG07 (WHO), QJ01XB01 (WHO), QJ51XB01 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) CA: ℞-only UK: POM (Prescription only) US: ℞-only EU: Rx-only
Pharmacokinetic data
Bioavailability	0%
Elimination half-life	5 hours
Identifiers
IUPAC name N-(4-amino-1-(1-(4-amino-1-oxo-1-(3,12,23-tris(2-aminoethyl)- 20-(1-hydroxyethyl)-6,9-diisobutyl-2,5,8,11,14,19,22-heptaoxo- 1,4,7,10,13,18-hexaazacyclotricosan-15-ylamino)butan-2-ylamino)- 3-hydroxybutan-2-ylamino)-1-oxobutan-2-yl)-N,5-dimethylheptanamide
CAS Number	1066-17-7 Y as salt: 8068-28-8 Y
PubChem CID	5311054
DrugBank	DB00803 Y
ChemSpider	4470591 Y
UNII	Z67X93HJG1 as salt: XW0E5YS77G Y
KEGG	D02138 Y as salt: D02049 Y
ChEMBL	ChEMBL501505 N
Chemical and physical data
Formula	C52H98N16O13
Molar mass	1155.455 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H]1C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC1)[C@H](O)C)CCN)CCN)CC(C)C)CC(C)C)CCN)CCN)[C@H](O)C)CCN)CCCC(C)CC
InChI InChI=1S/C52H98N16O13/c1-9-29(6)11-10-12-40(71)59-32(13-19-53)47(76)68-42(31(8)70)52(81)64-35(16-22-56)44(73)63-37-18-24-58-51(80)41(30(7)69)67-48(77)36(17-23-57)61-43(72)33(14-20-54)62-49(78)38(25-27(2)3)66-50(79)39(26-28(4)5)65-45(74)34(15-21-55)60-46(37)75/h27-39,41-42,69-70H,9-26,53-57H2,1-8H3,(H,58,80)(H,59,71)(H,60,75)(H,61,72)(H,62,78)(H,63,73)(H,64,81)(H,65,74)(H,66,79)(H,67,77)(H,68,76)/t29?,30-,31-,32+,33+,34+,35+,36+,37+,38+,39-,41+,42+/m1/s1 Y Key:YKQOSKADJPQZHB-QNPLFGSASA-N Y
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Angol

Főnév

colistin (tsz. colistins)

1. (gyógyszertan) kolisztin

További információk

• colistin - Szótár.net (en-hu)
• colistin - Sztaki (en-hu)
• colistin - Merriam–Webster
• colistin - Cambridge
• colistin - WordNet
• colistin - Яндекс (en-ru)
• colistin - Google (en-hu)
• colistin - Wikidata
• colistin - Wikipédia (angol)