demeclocycline

demeclocycline

Clinical data
Trade names	Declomycin
Other names	RP-10192, demethylchlortetracycline
AHFS/Drugs.com	Monograph
MedlinePlus	a682103
Routes of administration	Oral
ATC code	D06AA01 (WHO) J01AA01 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability	60–80%
Protein binding	41–50%
Metabolism	Hepatic
Elimination half-life	10–17 hours
Excretion	Renal
Identifiers
IUPAC name (2E,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylidene]-7-chloro-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-1,2,3,4,4a,5,5a,6,12,12a-decahydrotetracene-1,3,12-trione
CAS Number	127-33-3 Y 64-73-3 (HCl)
PubChem CID	54680690
DrugBank	DB00618 Y
ChemSpider	10482117 Y
UNII	5R5W9ICI6O
KEGG	D03680 Y
ChEBI	CHEBI:4392 Y
ChEMBL	ChEMBL1591 Y
Chemical and physical data
Formula	C21H21ClN2O8
Molar mass	464.855 g·mol−1
3D model (JSmol)	Interactive image
SMILES NC(=O)C1C(=O)[C@@]2(O)C(O)=C3C(=O)c4c(O)ccc(Cl)c4[C@@H](O)[C@H]3C[C@H]2C(C=1O)N(C)C
InChI InChI=1S/C21H21ClN2O8/c1-24(2)14-7-5-6-10(16(27)12-9(25)4-3-8(22)11(12)15(6)26)18(29)21(7,32)19(30)13(17(14)28)20(23)31/h3-4,6-7,14-15,25-26,28-29,32H,5H2,1-2H3,(H2,23,31)/t6-,7-,14-,15-,21-/m0/s1 Y Key:FMTDIUIBLCQGJB-SEYHBJAFSA-N Y
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Angol

Főnév

demeclocycline (tsz. demeclocyclines)

1. (gyógyszertan) demeklociklin

További információk

• demeclocycline - Szótár.net (en-hu)
• demeclocycline - Sztaki (en-hu)
• demeclocycline - Merriam–Webster
• demeclocycline - Cambridge
• demeclocycline - WordNet
• demeclocycline - Яндекс (en-ru)
• demeclocycline - Google (en-hu)
• demeclocycline - Wikidata
• demeclocycline - Wikipédia (angol)