desvenlafaxine

desvenlafaxine
Clinical data
Pronunciation	/dɛsˌvɛnləˈfæksiːn/; des-ven-lə-FAK-seen
Trade names	Pristiq, Desfax, Ellefore, others
Other names	O-desmethylvenlafaxine, WY-45233
AHFS/Drugs.com	Monograph
MedlinePlus	a608022
License data	US DailyMed: Desvenlafaxine;
Pregnancy; category	AU: B2;
Routes of; administration	By mouth
ATC code	N06AX23 (WHO) ;
Legal status
Legal status	AU: S4 (Prescription only); BR: Class C1 (Other controlled substances); CA: ℞-only; US: ℞-only;
Pharmacokinetic data
Bioavailability	80%
Protein binding	Low (30%)
Metabolism	CYP2C19, CYP3A4, (CYP2D6 is not involved)
Elimination half-life	11 h
Excretion	45% excreted unchanged in urine
Identifiers
	IUPAC name (RS)-4-[2-dimethylamino-1-(1-hydroxycyclohexyl); ethyl]phenol;
CAS Number	93413-62-8 ;
PubChem CID	125017;
IUPHAR/BPS	7158;
DrugBank	DB06700 ;
ChemSpider	111300 ;
UNII	NG99554ANW;
KEGG	D07793 ;
ChEBI	CHEBI:83527 ;
ChEMBL	ChEMBL1118 ;
Chemical and physical data
Formula	C16H25NO2
Molar mass	263.381 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES OC2(C(c1ccc(O)cc1)CN(C)C)CCCCC2;
	InChI InChI=1S/C16H25NO2/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16/h6-9,15,18-19H,3-5,10-12H2,1-2H3 ; Key:KYYIDSXMWOZKMP-UHFFFAOYSA-N ;
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