dextroamphetamine

dextroamphetamine
INN: Dexamfetamine

Clinical data
Pronunciation	/ˌdɛkstroʊæmˈfɛtəmiːn/
Trade names	Dexedrine, others
Other names	d-Amphetamine, (S)-Amphetamine, S(+)-Amphetamine
AHFS/Drugs.com	Monograph
MedlinePlus	a605027
License data	US DailyMed: Dextroamphetamine
Pregnancy category	AU: B3
Dependence liability	Physical: None Psychological: Moderate
Addiction liability	Moderate – high
Routes of administration	By mouth, transdermal, intravenous, insufflation, rectal
Drug class	Stimulant
ATC code	N06BA02 (WHO)
Legal status
Legal status	AU: S8 (Controlled drug) BR: Class A3 (Psychoactive drugs) CA: ℞-only / Schedule G (CDSA I) DE: Anlage III (Special prescription form required) UK: Class B US: Schedule II UN: Psychotropic Schedule II EU: Rx-only SE: Förteckning II
Pharmacokinetic data
Bioavailability	Oral: ~90%
Protein binding	15–40%
Metabolism	CYP2D6, DBH, FMO3
Onset of action	IR dosing: 0.5–1.5 hours XR dosing: 1.5–2 hours
Elimination half-life	9–11 hours pH-dependent: 7–34 hours
Duration of action	IR dosing: 3–6 hours XR dosing: 8–12 hours
Excretion	Kidney (45%); urinary pH-dependent
Identifiers
IUPAC name (2S)-1-Phenylpropan-2-amine
CAS Number	51-64-9 Y
PubChem CID	5826
IUPHAR/BPS	2147
DrugBank	DB01576 Y
ChemSpider	5621 Y
UNII	TZ47U051FI
KEGG	D03740 Y
ChEBI	CHEBI:4469 Y
ChEMBL	ChEMBL612 Y
Chemical and physical data
Formula	C9H13N
Molar mass	135.21 g·mol−1
3D model (JSmol)	Interactive image
Chirality	Dextrorotatory enantiomer
Density	0.913 g/cm3
Boiling point	201.5 °C (394.7 °F)
Solubility in water	20mg per ml
SMILES C[C@@H](Cc1ccccc1)N
InChI InChI=InChI=1S/C9H13N/c1-8(10)7-9-5-3-2-4-6-9/h2-6,8H,7,10H2,1H3/t8-/m0/s1 N Key:KWTSXDURSIMDCE-QMMMGPOBSA-N Y
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Angol

Főnév

dextroamphetamine (tsz. dextroamphetamines)

1. (gyógyszertan) dextroamfetamin

További információk

• dextroamphetamine - Szótár.net (en-hu)
• dextroamphetamine - Sztaki (en-hu)
• dextroamphetamine - Merriam–Webster
• dextroamphetamine - Cambridge
• dextroamphetamine - WordNet
• dextroamphetamine - Яндекс (en-ru)
• dextroamphetamine - Google (en-hu)
• dextroamphetamine - Wikidata
• dextroamphetamine - Wikipédia (angol)