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dopamine

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Dopamine
Skeletal formula of dopamine
Ball-and-stick model of the zwitterionic form of dopamine found in the crystal structure 
Clinical data
Trade namesIntropin, Dopastat, Revimine, others
Other names2-(3,4-Dihydroxyphenyl)ethylamine; 3,4-Dihydroxyphenethylamine; 3-hydroxytyramine; DA; Intropin; Revivan; Oxytyramine; Prolactin inhibiting factor; Prolactin inhibiting hormone
AHFS/Drugs.comMonograph
Routes of
administration
Intravenous
ATC code
Physiological data
Source tissuesSubstantia nigra; ventral tegmental area; many others
Target tissuesSystem-wide
ReceptorsD1, D2, D3, D4, D5, TAAR1
AgonistsDirect: apomorphine, bromocriptine
Indirect: cocaine, substituted amphetamine, cathinone, bupropion
AntagonistsNeuroleptics, metoclopramide, domperidone
MetabolismMAO, COMT, ALDH, DBH, MAO-A, MAO-B, COMT
Legal status
Legal status
  • EU: Rx-only
  • In general: ℞ (Prescription only)
Pharmacokinetic data
MetabolismMAO, COMT, ALDH, DBH, MAO-A, MAO-B, COMT
ExcretionKidney
Identifiers
  • 4-(2-Aminoethyl)benzene-1,2-diol
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
Chemical and physical data
FormulaC8H11NO2
Molar mass153.181 g·mol−1
3D model (JSmol)
Density1.26 g/cm3
Melting point128 °C (262 °F)
Boiling pointdecomposes
  • c1cc(c(cc1CCN)O)O
  • InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 checkY
  • Key:VYFYYTLLBUKUHU-UHFFFAOYSA-N checkY
  (verify)

Főnév

dopamine (tsz. dopamines)

  1. (gyógyszertan) dopamin