esketamine

esketamine

Clinical data
Trade names	Spravato, Ketanest, Spravado, others
Other names	(S)-Ketamine; S(+)-Ketamine; JNJ-54135419
AHFS/Drugs.com	Monograph
MedlinePlus	a619017
License data	EU EMA: by INN US DailyMed: Esketamine US FDA: Esketamine
Pregnancy category	AU: B3
Addiction liability	Moderate
Routes of administration	Intranasal, intravenous
Drug class	NMDA receptor antagonist; Antidepressant; General anesthetic; Dissociative hallucinogen; Analgesic
ATC code	N01AX14 (WHO) N06AX27 (WHO)
Legal status
Legal status	AU: S8 (Controlled drug) BR: Class B1 (Psychoactive drugs) CA: ℞-only UK: POM (Prescription only) US: Schedule III EU: Rx-only In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability	Intranasal: 30–50%
Elimination half-life	5 hours
Identifiers
IUPAC name (S)-2-(2-chlorophenyl)-2-(methylamino)cyclohexanone
CAS Number	33643-46-8 Y HCl: 33643-47-9 Y
PubChem CID	182137
IUPHAR/BPS	9152
DrugBank	DB01221 Y HCl: DBSALT002086 Y
ChemSpider	158414 Y HCl: 26332012 Y
UNII	50LFG02TXD HCl: L8P1H35P2Z Y
KEGG	D07283 Y HCl: D10627 Y
ChEBI	CHEBI:60799 Y HCl: CHEBI:60800 Y
ChEMBL	ChEMBL395091 Y HCl: ChEMBL2364609 Y
PDB ligand	JC9 (PDBe, RCSB PDB)
Chemical and physical data
Formula	C13H16ClNO
Molar mass	237.727 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN[C@]1(c2ccccc2Cl)CCCCC1=O
InChI InChI=1S/C13H16ClNO/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14/h2-3,6-7,15H,4-5,8-9H2,1H3/t13-/m0/s1 N Key:YQEZLKZALYSWHR-ZDUSSCGKSA-N N
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Angol

Főnév

esketamine (tsz. esketamines)

1. (gyógyszertan) eszketamin

További információk

• esketamine - Szótár.net (en-hu)
• esketamine - Sztaki (en-hu)
• esketamine - Merriam–Webster
• esketamine - Cambridge
• esketamine - WordNet
• esketamine - Яндекс (en-ru)
• esketamine - Google (en-hu)
• esketamine - Wikidata
• esketamine - Wikipédia (angol)