everolimus

everolimus

Clinical data
Pronunciation	Everolimus /ˌɛvəˈroʊləməs/
Trade names	Afinitor, Zortress
Other names	42-O-(2-hydroxyethyl)rapamycin, RAD001
AHFS/Drugs.com	Monograph
MedlinePlus	a609032
License data	US DailyMed: Everolimus
Pregnancy category	AU: C
Routes of administration	By mouth
ATC code	L01EG02 (WHO) L04AH02 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) US: ℞-only EU: Rx-only In general: ℞ (Prescription only)
Pharmacokinetic data
Elimination half-life	~30 hours
Identifiers
IUPAC name Dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0 hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
CAS Number	159351-69-6 Y
PubChem CID	6442177
DrugBank	DB01590 Y
ChemSpider	21106307 Y
UNII	9HW64Q8G6G
KEGG	D02714 Y
ChEBI	CHEBI:68478
ChEMBL	ChEMBL1908360 N
Chemical and physical data
Formula	C53H83NO14
Molar mass	958.24 g·mol−1
3D model (JSmol)	Interactive image
SMILES OCCO[C@@H]1CC[C@H](C[C@H]1OC)C[C@@H](C)[C@@H]4CC(=O)[C@H](C)/C=C(\C)[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(/C)[C@@H](OC)C[C@@H]2CC[C@@H](C)[C@@](O)(O2)C(=O)C(=O)N3CCCC[C@H]3C(=O)O4
InChI InChI=1S/C53H83NO14/c1-32-16-12-11-13-17-33(2)44(63-8)30-40-21-19-38(7)53(62,68-40)50(59)51(60)54-23-15-14-18-41(54)52(61)67-45(35(4)28-39-20-22-43(66-25-24-55)46(29-39)64-9)31-42(56)34(3)27-37(6)48(58)49(65-10)47(57)36(5)26-32/h11-13,16-17,27,32,34-36,38-41,43-46,48-49,55,58,62H,14-15,18-26,28-31H2,1-10H3/b13-11+,16-12+,33-17+,37-27+/t32-,34-,35-,36-,38-,39+,40+,41+,43-,44+,45+,46-,48-,49+,53-/m1/s1 Y Key:HKVAMNSJSFKALM-GKUWKFKPSA-N Y
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Angol

Főnév

everolimus (tsz. everolimuses)

1. (gyógyszertan) everolimusz

További információk

• everolimus - Szótár.net (en-hu)
• everolimus - Sztaki (en-hu)
• everolimus - Merriam–Webster
• everolimus - Cambridge
• everolimus - WordNet
• everolimus - Яндекс (en-ru)
• everolimus - Google (en-hu)
• everolimus - Wikidata
• everolimus - Wikipédia (angol)