hydroxycarbamide

hydroxycarbamide
Clinical data
Trade names	Droxia, Hydrea, Siklos, others
Other names	Hydroxyurea (USAN US)
AHFS/Drugs.com	Monograph
MedlinePlus	a682004
License data	US DailyMed: Hydroxyurea;
Pregnancy; category	AU: D;
Routes of; administration	By mouth
ATC code	L01XX05 (WHO) ;
Legal status
Legal status	AU: S4 (Prescription only); CA: ℞-only; UK: POM (Prescription only); US: ℞-only; EU: Rx-only; In general: ℞ (Prescription only);
Pharmacokinetic data
Metabolism	Liver (to CO2 and urea)
Elimination half-life	2–4 hours
Excretion	Kidney and lungs
Identifiers
	IUPAC name Hydroxyurea;
CAS Number	127-07-1 ;
PubChem CID	3657;
IUPHAR/BPS	6822;
DrugBank	DB01005 ;
ChemSpider	3530 ;
UNII	X6Q56QN5QC;
KEGG	D00341 ;
ChEBI	CHEBI:44423 ;
ChEMBL	ChEMBL467 ;
NIAID ChemDB	006310;
Chemical and physical data
Formula	CH4N2O2
Molar mass	76.055 g·mol−1
3D model (JSmol)	Interactive image;
Melting point	133 to 136 °C (271 to 277 °F)
	SMILES O=C(N)NO;
	InChI InChI=1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4) ; Key:VSNHCAURESNICA-UHFFFAOYSA-N ;
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Angol

hydroxycarbamide (tsz. hydroxycarbamides)