hydroxyzine

hydroxyzine

Clinical data
Pronunciation	/haɪˈdrɒksɪziːn/
Trade names	Atarax, Vistaril, others
Other names	UCB-4492
AHFS/Drugs.com	Monograph
MedlinePlus	a682866
License data	US DailyMed: Hydroxyzine
Dependence liability	None
Routes of administration	By mouth, intramuscular
Drug class	First-generation antihistamine
ATC code	N05BB01 (WHO) N05BB51 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) CA: ℞-only UK: POM (Prescription only) US: ℞-only EU: Rx-only In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability	High
Protein binding	93%
Metabolism	Liver
Metabolites	Cetirizine, others
Elimination half-life	Adults: 20.0 hours Elderly: 29.3 hours Children: 7.1 hours
Excretion	Urine, feces
Identifiers
IUPAC name (±)-2-(2-{4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl}ethoxy)ethanol
CAS Number	68-88-2 Y 10246-75-0 (pamoate) as HCl: 2192-20-3
PubChem CID	3658 as HCl: 91513
IUPHAR/BPS	7199
DrugBank	DB00557 Y as HCl: DBSALT000343
ChemSpider	3531 Y as HCl: 82634
UNII	30S50YM8OG as HCl: 76755771U3
KEGG	D08054 Y as HCl: D00672
ChEBI	CHEBI:5818 Y as HCl: CHEBI:5819
ChEMBL	ChEMBL896 Y as HCl: ChEMBL3186993
Chemical and physical data
Formula	C21H27ClN2O2
Molar mass	374.909 g·mol−1
3D model (JSmol)	Interactive image
SMILES Clc1ccc(cc1)C(c2ccccc2)N3CCN(CC3)CCOCCO
InChI InChI=1S/C21H27ClN2O2/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25/h1-9,21,25H,10-17H2 Y Key:ZQDWXGKKHFNSQK-UHFFFAOYSA-N Y
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Angol

Főnév

hydroxyzine (tsz. hydroxyzines)

1. (gyógyszertan) hidroxizin

További információk

• hydroxyzine - Szótár.net (en-hu)
• hydroxyzine - Sztaki (en-hu)
• hydroxyzine - Merriam–Webster
• hydroxyzine - Cambridge
• hydroxyzine - WordNet
• hydroxyzine - Яндекс (en-ru)
• hydroxyzine - Google (en-hu)
• hydroxyzine - Wikidata
• hydroxyzine - Wikipédia (angol)