levocetirizine

levocetirizine

Clinical data
Trade names	Xyzal, Levazyr, others
Other names	Levocetirizine dihydrochloride
AHFS/Drugs.com	Monograph
MedlinePlus	a607056
License data	US DailyMed: Levocetirizine
Routes of administration	By mouth
Drug class	Second generation antihistamines
ATC code	R06AE09 (WHO)
Legal status
Legal status	UK: POM (Prescription only) US: OTC / Rx-only
Pharmacokinetic data
Bioavailability	High
Protein binding	91–92%
Metabolism	Minimal (less than 14%, primarily CYP3A4)
Elimination half-life	8 to 9 hours
Excretion	Urine: 85% Feces: 12.9%
Identifiers
IUPAC name 2-(2-{4-[(R)-(4-Chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid
CAS Number	130018-77-8 N
PubChem CID	1549000
IUPHAR/BPS	1214
DrugBank	DB06282 Y
ChemSpider	1266001 Y
UNII	6U5EA9RT2O
KEGG	D07402 Y as salt: D08118 Y
ChEBI	CHEBI:94559
ChEMBL	ChEMBL1201191 N
PDB ligand	LCR (PDBe, RCSB PDB)
Chemical and physical data
Formula	C21H25ClN2O3
Molar mass	388.892 g·mol−1
3D model (JSmol)	Interactive image
SMILES Clc1ccc(cc1)[C@H](N2CCN(CCOCC(=O)O)CC2)c3ccccc3
InChI InChI=1S/C21H25ClN2O3/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26/h1-9,21H,10-16H2,(H,25,26)/t21-/m1/s1 Y Key:ZKLPARSLTMPFCP-OAQYLSRUSA-N Y
NY (what is this?)  (verify)

Angol

Főnév

levocetirizine (tsz. levocetirizines)

1. (gyógyszertan) levocetirizin

További információk

• levocetirizine - Szótár.net (en-hu)
• levocetirizine - Sztaki (en-hu)
• levocetirizine - Merriam–Webster
• levocetirizine - Cambridge
• levocetirizine - WordNet
• levocetirizine - Яндекс (en-ru)
• levocetirizine - Google (en-hu)
• levocetirizine - Wikidata
• levocetirizine - Wikipédia (angol)