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lisuride

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lisuride
Clinical data
Trade namesDopergin, others
Other namesLysuride; Mesorgydin; Methylergol carbamide; 1,1-Diethyl-3-(6-methyl-9,10-didehydroergolin-8α-yl)urea
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Oral
Drug classSerotonin receptor agonist; Dopamine receptor agonist
ATC code
Legal status
Legal status
  • BR: Class C1 (Other controlled substances)
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability10–20%
Protein binding60–70%
MetabolismHepatic
MetabolitesMore than 15 known
Elimination half-life2 hours
ExcretionRenal and biliary in equal amounts
Identifiers
  • 1,1-Diethyl-3-(7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinolin-9-yl)-urea
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
Chemical and physical data
FormulaC20H26N4O
Molar mass338.455 g·mol−1
3D model (JSmol)
  • [H][C@@]12Cc3c[nH]c4cccc(C1=C[C@H](NC(=O)N(CC)CC)CN2C)c34
  • InChI=1S/C20H26N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,10-11,14,18,21H,4-5,9,12H2,1-3H3,(H,22,25)/t14-,18+/m0/s1 checkY
  • Key:BKRGVLQUQGGVSM-KBXCAEBGSA-N checkY
  (verify)


Főnév

lisuride (tsz. lisurides)

  1. (gyógyszertan) lizurid