methamphetamine

methamphetamine
INN: Metamfetamine

Clinical data
Pronunciation	/ˌmɛθæmˈfɛtəmiːn/ (METH-am-FET-ə-meen), /ˌmɛθəmˈfɛtəmiːn/ (METH-əm-FET-ə-meen), /ˌmɛθəmˈfɛtəmən/ (METH-əm-FET-ə-mən)
Trade names	Desoxyn, others
Other names	N-methylamphetamine, N,α-dimethylphenethylamine, desoxyephedrine. Street title: Batu, Bikers Coffee, Black Beauties, Chalk, Chicken Feed, Crank, Crystal, Glass, Go-Fast, Hiropon, Ice, Meth, Methlies Quick, Poor Man's Cocaine, Shabu, Shards, Speed, Stove Top, Tina, Trash, Tweak, Uppers, Ventana, Vidrio, Yaba, Yellow Barn
AHFS/Drugs.com	Monograph
Dependence liability	Physical: None Psychological: Very high
Addiction liability	Very high
Routes of administration	By mouth, intravenous, intramuscular, subcutaneous, inhalation, insufflation, rectal, vaginal
ATC code	N06BA03 (WHO)
Legal status
Legal status	AU: S8 (Controlled drug) BR: Class F2 (Prohibited psychotropics) CA: Schedule I DE: Anlage II (Authorized trade only, not prescriptible) NZ: Class A UK: Class A US: Schedule II UN: Psychotropic Schedule II SE: Förteckning II
Pharmacokinetic data
Bioavailability	Oral: 67% Intranasal: 79% Inhalation: 67–90% Intravenous: 100%
Protein binding	Varies widely
Metabolism	CYP2D6 and FMO3
Metabolites	• Amphetamine • Pholedrine • N-Hydroxymethamphetamine
Onset of action	Oral: 3 hours (peak) Intranasal: <15 minutes Inhalation: <18 minutes Intravenous: <15 minutes
Elimination half-life	9–12 hours (range 5–30 hours); irrespective of route
Duration of action	8–12 hours
Excretion	Primarily kidney
Identifiers
IUPAC name (RS)-N-methyl-1-phenylpropan-2-amine
CAS Number	537-46-2 (dl)-Methamphetamine hydrochloride: 300-42-5
PubChem CID	1206
IUPHAR/BPS	4803
DrugBank	DB01577
ChemSpider	1169
UNII	44RAL3456C (dl)-Methamphetamine hydrochloride: 24GNZ56D62
KEGG	D08187
ChEBI	CHEBI:6809
ChEMBL	ChEMBL1201201
PDB ligand	B40 (PDBe, RCSB PDB)
Chemical and physical data
Formula	C10H15N
Molar mass	149.237 g·mol−1
3D model (JSmol)	Interactive image
Chirality	Racemic mixture
Melting point	170 °C (338 °F)
Boiling point	212 °C (414 °F) at 760 mmHg
SMILES CNC(C)Cc1ccccc1
InChI InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3 Key:MYWUZJCMWCOHBA-UHFFFAOYSA-N
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Angol

Főnév

methamphetamine (tsz. methamphetamines)

1. (gyógyszertan) metamfetamin

További információk

• methamphetamine - Szótár.net (en-hu)
• methamphetamine - Sztaki (en-hu)
• methamphetamine - Merriam–Webster
• methamphetamine - Cambridge
• methamphetamine - WordNet
• methamphetamine - Яндекс (en-ru)
• methamphetamine - Google (en-hu)
• methamphetamine - Wikidata
• methamphetamine - Wikipédia (angol)