minocycline

minocycline

Clinical data
Trade names	Minocin, others
AHFS/Drugs.com	Monograph
MedlinePlus	a682101
License data	US DailyMed: Minocycline
Pregnancy category	AU: D
Routes of administration	By mouth, intravenous, topical
Drug class	Antibiotic; Tetracycline antibiotic
ATC code	J01AA08 (WHO) A01AB23 (WHO), D10AF07 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability	90–100%
Protein binding	70–75%
Metabolism	Liver
Elimination half-life	15.5 h (11–26 h)
Excretion	Mostly fecal, 10–15% renal
Identifiers
IUPAC name (2E,4S,4aR,5aS,12aR)-2-(Amino-hydroxy-methylidene)-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4a,5,5a,6- tetrahydro-4H-tetracene-1,3,12-trione
CAS Number	10118-90-8
PubChem CID	54675783
DrugBank	DB01017
ChemSpider	16735907
UNII	FYY3R43WGO
KEGG	D05045
ChEBI	CHEBI:50694
ChEMBL	ChEMBL1434
Chemical and physical data
Formula	C23H27N3O7
Molar mass	457.483 g·mol−1
3D model (JSmol)	Interactive image
Specific rotation	$[\alpha ]_{D}^{25}$ = −166°
Solubility in water	Low
SMILES CN(C)c1ccc(c2c1C[C@H]3C[C@H]4[C@@H](C(=C(C(=O)[C@]4(C(=C3C2=O)O)O)C(=O)N)O)N(C)C)O
InChI InChI=1S/C23H27N3O7/c1-25(2)12-5-6-13(27)15-10(12)7-9-8-11-17(26(3)4)19(29)16(22(24)32)21(31)23(11,33)20(30)14(9)18(15)28/h5-6,9,11,17,27,29-30,33H,7-8H2,1-4H3,(H2,24,32)/t9-,11-,17-,23-/m0/s1 Key:DYKFCLLONBREIL-KVUCHLLUSA-N

Angol

Főnév

minocycline (tsz. minocyclines)

1. (gyógyszertan) minociklin

További információk

• minocycline - Szótár.net (en-hu)
• minocycline - Sztaki (en-hu)
• minocycline - Merriam–Webster
• minocycline - Cambridge
• minocycline - WordNet
• minocycline - Яндекс (en-ru)
• minocycline - Google (en-hu)
• minocycline - Wikidata
• minocycline - Wikipédia (angol)