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norepinephrine

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norepinephrine
Skeletal formula of noradrenaline
Ball-and-stick model of the zwitterionic form of noradrenaline found in the crystal structure
Clinical data
Other names
  • NE, NA,
  • Noradrenaline,
  • (R)-(–)-Norepinephrine,
  • l-1-(3,4-Dihydroxyphenyl)-2-aminoethanol
  • 3,4,β-Trihydroxyphenethylamine
Physiological data
Source tissueslocus coeruleus; sympathetic nervous system; adrenal medulla
Target tissuessystem-wide
Receptorsα1, α2, β1, β3
Agonistssympathomimetic drugs, clonidine, isoprenaline
AntagonistsTricyclic antidepressants, beta blockers, antipsychotics
Precursordopamine
Biosynthesisdopamine β-monooxygenase
MetabolismMAO-A; COMT
Identifiers
  • (R)-4-(2-amino-1-hydroxyethyl)benzene-1,2-diol
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
Chemical and physical data
FormulaC8H11NO3
Molar mass169.18 g·mol−1
3D model (JSmol)
  • NC[C@H](O)c1cc(O)c(O)cc1
  • InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1
  • Key:SFLSHLFXELFNJZ-QMMMGPOBSA-N



Főnév

norepinephrine (tsz. norepinephrines)

  1. (gyógyszertan) noradrenalin