nortriptyline

nortriptyline

Clinical data
Trade names	Aventyl, others
Other names	Desitriptyline; ELF-101; E.L.F. 101; N-7048
AHFS/Drugs.com	Monograph
MedlinePlus	a682620
License data	US DailyMed: Nortriptyline
Pregnancy category	AU: C
Routes of administration	By mouth
Drug class	Tricyclic antidepressant (TCA)
ATC code	N06AA10 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) BR: Class C1 (Other controlled substances) CA: ℞-only US: ℞-only
Pharmacokinetic data
Bioavailability	32–79%
Protein binding	92%
Metabolism	Liver
Metabolites	10-E-Hydroxynortriptyline
Elimination half-life	18–44 hours (mean 30 hours)
Excretion	Urine: 40% Feces: minor
Identifiers
IUPAC name 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine
CAS Number	72-69-5 Y 894-71-3
PubChem CID	4543
IUPHAR/BPS	2404
DrugBank	DB00540 Y
ChemSpider	4384 Y
UNII	BL03SY4LXB
KEGG	D08288 Y
ChEBI	CHEBI:7640 Y
ChEMBL	ChEMBL445 Y
Chemical and physical data
Formula	C19H21N
Molar mass	263.384 g·mol−1
3D model (JSmol)	Interactive image
SMILES c3cc2c(/C(c1c(cccc1)CC2)=C/CCNC)cc3
InChI InChI=1S/C19H21N/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19/h2-5,7-11,20H,6,12-14H2,1H3 Y Key:PHVGLTMQBUFIQQ-UHFFFAOYSA-N Y
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Angol

Főnév

nortriptyline (tsz. nortriptylines)

1. (gyógyszertan) nortriptilin

További információk

• nortriptyline - Szótár.net (en-hu)
• nortriptyline - Sztaki (en-hu)
• nortriptyline - Merriam–Webster
• nortriptyline - Cambridge
• nortriptyline - WordNet
• nortriptyline - Яндекс (en-ru)
• nortriptyline - Google (en-hu)
• nortriptyline - Wikidata
• nortriptyline - Wikipédia (angol)