prochlorperazine

prochlorperazine
Clinical data
Trade names	Compazine, Stemetil, others
AHFS/Drugs.com	Monograph
MedlinePlus	a682116
License data	US DailyMed: Prochlorperazine;
Pregnancy; category	AU: C;
Routes of; administration	Oral administration, rectal administration, intramuscular injection, intravenous injection (IV)
Drug class	Typical antipsychotic
ATC code	N05AB04 (WHO) ;
Legal status
Legal status	AU: S4 (Prescription only) / S3; BR: Class C1 (Other controlled substances); UK: POM (Prescription only) / P; US: ℞-only;
Pharmacokinetic data
Bioavailability	Unknown, but presumed substantial
Protein binding	91–99%
Metabolism	Mainly Liver (CYP2D6 and/or CYP3A4)
Elimination half-life	4–8 hours, differs with the method of administration
Excretion	Bile duct, (colored) inactive metabolites in urine
Identifiers
	IUPAC name 2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine;
CAS Number	58-38-8 ;
PubChem CID	4917;
IUPHAR/BPS	7279;
DrugBank	DB00433 ;
ChemSpider	4748 ;
UNII	YHP6YLT61T;
KEGG	D00493 ;
ChEBI	CHEBI:8435 ;
ChEMBL	ChEMBL728 ;
Chemical and physical data
Formula	C20H24ClN3S
Molar mass	373.943 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Clc2cc1N(c3c(Sc1cc2)cccc3)CCCN4CCN(C)CC4;
	InChI InChI=1S/C20H24ClN3S/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3 ; Key:WIKYUJGCLQQFNW-UHFFFAOYSA-N ;
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Angol

prochlorperazine (tsz. prochlorperazines)