quetiapine

quetiapine

Clinical data
Pronunciation	kwi-TY-ə-peen
Trade names	Seroquel, Seroquel Xr, others
AHFS/Drugs.com	Monograph
MedlinePlus	a698019
License data	US DailyMed: Quetiapine
Pregnancy category	AU: B3
Routes of administration	By mouth
Drug class	Atypical antipsychotic
ATC code	N05AH04 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) BR: Class C1 (Other controlled substances) CA: ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability	100%
Protein binding	83%
Metabolism	Liver via CYP3A4-catalysed sulfoxidation to its active metabolite norquetiapine (N-desalkylquetiapine)
Elimination half-life	7 hours (parent compound); 9–12 hours (active metabolite, norquetiapine)
Excretion	Kidney (73%), feces (20%)
Identifiers
IUPAC name 2-(2-(4-Dibenzo[b,f][1,4]thiazepine-11-yl-1-piperazinyl)ethoxy)ethanol
CAS Number	111974-69-7
PubChem CID	5002
IUPHAR/BPS	50
DrugBank	DB01224
ChemSpider	4827
UNII	BGL0JSY5SI
KEGG	D08456
ChEBI	CHEBI:8707
ChEMBL	ChEMBL716
Chemical and physical data
Formula	C21H25N3O2S
Molar mass	383.51 g·mol−1
3D model (JSmol)	Interactive image
Solubility in water	3.29 mg/mL (20 °C)
SMILES N\1=C(\c3c(Sc2c/1cccc2)cccc3)N4CCN(CCOCCO)CC4
InChI InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 Key:URKOMYMAXPYINW-UHFFFAOYSA-N
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Angol

Főnév

quetiapine (tsz. quetiapines)

1. (gyógyszertan) kvetiapin

További információk

• quetiapine - Szótár.net (en-hu)
• quetiapine - Sztaki (en-hu)
• quetiapine - Merriam–Webster
• quetiapine - Cambridge
• quetiapine - WordNet
• quetiapine - Яндекс (en-ru)
• quetiapine - Google (en-hu)
• quetiapine - Wikidata
• quetiapine - Wikipédia (angol)