quinine

quinine

Clinical data
Pronunciation	US: /ˈkwaɪnaɪn/, /kwɪˈniːn/ or UK: /ˈkwɪniːn/ KWIN-een
Trade names	Qualaquin, Quinbisul, others
AHFS/Drugs.com	Monograph
MedlinePlus	a682322
License data	US DailyMed: Quinine US FDA: Quinine
Pregnancy category	AU: D
Routes of administration	By mouth, intramuscular, intravenous, rectal
ATC code	M09AA01 (WHO) P01BC01 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) CA: ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Protein binding	70–95%
Metabolism	Liver (mostly CYP3A4 and CYP2C19-mediated)
Elimination half-life	8–14 hours (adults), 6–12 hours (children)
Excretion	Kidney (20%)
Identifiers
IUPAC name (R)-(6-Methoxyquinolin-4-yl)[(1S,2S,4S,5R)-5-vinylquinuclidin-2-yl]methanol
CAS Number	130-95-0 Y
PubChem CID	8549
IUPHAR/BPS	2510
DrugBank	DB00468 Y
ChemSpider	84989 Y
UNII	A7V27PHC7A
KEGG	D08460 Y
ChEBI	CHEBI:15854 N
ChEMBL	ChEMBL170 Y
Chemical and physical data
Formula	C20H24N2O2
Molar mass	324.424 g·mol−1
3D model (JSmol)	Interactive image
Melting point	177 °C (351 °F)
SMILES [H][C@@]1([C@@H](C2=CC=NC3=CC=C(C=C23)OC)O)C[C@@H]4CC[N@]1C[C@@H]4C=C
InChI InChI=1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19-,20+/m0/s1 Y Key:LOUPRKONTZGTKE-WZBLMQSHSA-N Y
NY (what is this?)  (verify)

Angol

Főnév

quinine (tsz. quinines)

1. (gyógyszertan) kinin

További információk

• quinine - Szótár.net (en-hu)
• quinine - Sztaki (en-hu)
• quinine - Merriam–Webster
• quinine - Cambridge
• quinine - WordNet
• quinine - Яндекс (en-ru)
• quinine - Google (en-hu)
• quinine - Wikidata
• quinine - Wikipédia (angol)