rufinamide

rufinamide
Clinical data
Trade names	Banzel, Inovelon
AHFS/Drugs.com	Monograph
MedlinePlus	a609001
License data	EU EMA: by INN; US DailyMed: Rufinamide; US FDA: Rufinamide;
Pregnancy; category	AU: B3;
Routes of; administration	By mouth
ATC code	N03AF03 (WHO) ;
Legal status
Legal status	BR: Class C1 (Other controlled substances); UK: POM (Prescription only); US: ℞-only; In general: ℞ (Prescription only);
Pharmacokinetic data
Bioavailability	85% (under fed conditions); tmax = 4–6 hours
Protein binding	34%
Metabolism	Carboxylesterase-mediated hydrolysis (CYP not involved)
Metabolites	Inactive
Elimination half-life	6–10 hours
Excretion	Urine (85%)
Identifiers
	IUPAC name 1-(2,6-Difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide;
CAS Number	106308-44-5 ;
PubChem CID	129228;
IUPHAR/BPS	7470;
ChemSpider	114471 ;
UNII	WFW942PR79;
KEGG	D05775;
ChEMBL	ChEMBL1201754 ;
Chemical and physical data
Formula	C10H8F2N4O
Molar mass	238.197806326 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(c1nnn(c1)Cc2c(F)cccc2F)N;
	InChI InChI=1S/C10H8F2N4O/c11-7-2-1-3-8(12)6(7)4-16-5-9(10(13)17)14-15-16/h1-3,5H,4H2,(H2,13,17) ; Key:POGQSBRIGCQNEG-UHFFFAOYSA-N ;
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Angol

rufinamide (tsz. rufinamides)