solifenacin

solifenacin

Clinical data
Trade names	Vesicare, Vesicare LS
Other names	YM905
AHFS/Drugs.com	Monograph
MedlinePlus	a605019
License data	US DailyMed: Solifenacin
Pregnancy category	AU: B3
Routes of administration	By mouth
ATC code	G04BD08 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability	90%
Protein binding	98%
Metabolism	CYP3A4
Metabolites	Glucuronide, N-oxide, others
Elimination half-life	45 to 68 hours
Excretion	Kidney (69.2%) and fecal (22.5%)
Identifiers
IUPAC name (3R)-1-Azabicyclo[2 2 2]oct-3-yl (1S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
CAS Number	242478-37-1 N
PubChem CID	154059
IUPHAR/BPS	7483
DrugBank	DB01591 Y
ChemSpider	135771 N
UNII	A8910SQJ1U
KEGG	DG00481 N
ChEMBL	ChEMBL1734 N
Chemical and physical data
Formula	C23H26N2O2
Molar mass	362.473 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1CN2CCC1[C@H](C2)OC(=O)N3CCC4=CC=CC=C4[C@@H]3C5=CC=CC=C5
InChI InChI=1S/C23H26N2O2/c26-23(27-21-16-24-13-10-18(21)11-14-24)25-15-12-17-6-4-5-9-20(17)22(25)19-7-2-1-3-8-19/h1-9,18,21-22H,10-16H2/t21-,22-/m0/s1 N Key:FBOUYBDGKBSUES-VXKWHMMOSA-N N
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Angol

Főnév

solifenacin (tsz. solifenacins)

1. (gyógyszertan) szolifenacin

További információk

• solifenacin - Szótár.net (en-hu)
• solifenacin - Sztaki (en-hu)
• solifenacin - Merriam–Webster
• solifenacin - Cambridge
• solifenacin - WordNet
• solifenacin - Яндекс (en-ru)
• solifenacin - Google (en-hu)
• solifenacin - Wikidata
• solifenacin - Wikipédia (angol)