tigecycline

tigecycline

Clinical data
Pronunciation	/ˌtaɪɡəˈsaɪkliːn/
Trade names	Tygacil
AHFS/Drugs.com	Monograph
MedlinePlus	a614002
License data	US DailyMed: Tigecycline
Pregnancy category	AU: D
Routes of administration	Intravenous (IV)
ATC code	J01AA12 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) US: ℞-only EU: Rx-only
Pharmacokinetic data
Protein binding	71–89%
Metabolism	Not metabolized
Elimination half-life	42.4 hours
Excretion	59% Bile duct, 33% kidney
Identifiers
IUPAC name N-[(5aR,6aS,7S,9Z,10aS)-9-(amino-hydroxy-methylidene)-4,7-bis(dimethylamino)-1,10a,12-trihydroxy-8,10,11-trioxo-5a,6,6a,7-tetrahydro-5H-tetracen-2-yl]-2-(tert-butylamino) acetamide
CAS Number	220620-09-7 Y
PubChem CID	5282044
DrugBank	DB00560 Y
ChemSpider	10482314 Y
UNII	70JE2N95KR
KEGG	D01079 Y
ChEBI	CHEBI:149836 Y
ChEMBL	ChEMBL376140 Y
Chemical and physical data
Formula	C29H39N5O8
Molar mass	585.658 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(C)(C)NCC(=O)Nc1cc(c2C[C@H]3C[C@H]4[C@H](N(C)C)C(\O)=C(\C(N)=O)C(=O)[C@@]4(O)C(/O)=C3/C(=O)c2c1O)N(C)C
InChI InChI=1S/C29H39N5O8/c1-28(2,3)31-11-17(35)32-15-10-16(33(4)5)13-8-12-9-14-21(34(6)7)24(38)20(27(30)41)26(40)29(14,42)25(39)18(12)23(37)19(13)22(15)36/h10,12,14,21,31,36,38-39,42H,8-9,11H2,1-7H3,(H2,30,41)(H,32,35)/t12-,14-,21-,29-/m0/s1 Y Key:FPZLLRFZJZRHSY-HJYUBDRYSA-N Y
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Angol

Főnév

tigecycline (tsz. tigecyclines)

1. (gyógyszertan) tigeciklin

További információk

• tigecycline - Szótár.net (en-hu)
• tigecycline - Sztaki (en-hu)
• tigecycline - Merriam–Webster
• tigecycline - Cambridge
• tigecycline - WordNet
• tigecycline - Яндекс (en-ru)
• tigecycline - Google (en-hu)
• tigecycline - Wikidata
• tigecycline - Wikipédia (angol)