tizanidine

tizanidine

Clinical data
Pronunciation	/taɪˈzænɪdiːn/ tye-ZAN-i-deen
Trade names	Zanaflex, Sirdalud, and others
Other names	4-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-8-thia-7,9-diazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amine
AHFS/Drugs.com	Monograph
MedlinePlus	a601121
License data	US DailyMed: Tizanidine
Routes of administration	By mouth
Drug class	α2-adrenergic receptor agonist
ATC code	M03BX02 (WHO)
Legal status
Legal status	UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability	~40%
Protein binding	~30%
Metabolism	Liver (CYP1A2, 95%)
Elimination half-life	2.54 hours (tizanidine), 20–40 hours (inactive metabolites)
Excretion	Urine (60%), feces (20%)
Identifiers
IUPAC name 5-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)benzo[c] [1,2,5]thiadiazol-4-amine
CAS Number	51322-75-9 Y
PubChem CID	5487
DrugBank	DB00697 Y
ChemSpider	5287 Y
UNII	6AI06C00GW
KEGG	D08611 Y as HCl: D00776 Y
ChEMBL	ChEMBL1079 Y
Chemical and physical data
Formula	C9H8ClN5S
Molar mass	253.708 g·mol−1
3D model (JSmol)	Interactive image
SMILES Clc1ccc3nsnc3c1NC/2=N/CCN\2
InChI InChI=1S/C9H8ClN5S/c10-5-1-2-6-8(15-16-14-6)7(5)13-9-11-3-4-12-9/h1-2H,3-4H2,(H2,11,12,13) Y Key:XFYDIVBRZNQMJC-UHFFFAOYSA-N Y
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Angol

Főnév

tizanidine (tsz. tizanidines)

1. (gyógyszertan) tizanidin

További információk

• tizanidine - Szótár.net (en-hu)
• tizanidine - Sztaki (en-hu)
• tizanidine - Merriam–Webster
• tizanidine - Cambridge
• tizanidine - WordNet
• tizanidine - Яндекс (en-ru)
• tizanidine - Google (en-hu)
• tizanidine - Wikidata
• tizanidine - Wikipédia (angol)