ulipristal

ulipristal
Clinical data
Trade names	Ella, EllaOne, Esmya, others
Other names	CDB-2914; 11β-[4-(Dimethylamino)phenyl]-17α-acetoxy-19-norpregna-4,9-diene-3,20-dione
AHFS/Drugs.com	Monograph
License data	US DailyMed: Ulipristal acetate;
Routes of; administration	By mouth
Drug class	Selective progesterone receptor modulator
ATC code	G03AD02 (WHO) G03XB02 (WHO);
Legal status
Legal status	AU: S4 (Prescription only); UK: POM (Prescription only) / P; US: ℞-only; EU: Rx-only;
Pharmacokinetic data
Bioavailability	Nearly 100%
Protein binding	96.7–99.5%
Metabolism	Likely CYP3A4
Elimination half-life	32 hours
Excretion	ca. 90% with feces
Identifiers
	IUPAC name [(8S,11R,13S,14S,17R)-17-acetyl-11-[4-(dimethylamino)phenyl]-13-methyl-3-oxo-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl] acetate;
CAS Number	126784-99-4 ;
PubChem CID	130904;
IUPHAR/BPS	7460;
DrugBank	DB08867 ;
ChemSpider	115762 ;
UNII	YF7V70N02B;
KEGG	D09687;
ChEBI	CHEBI:71025 ;
ChEMBL	ChEMBL260538 ;
Chemical and physical data
Formula	C30H37NO4
Molar mass	475.629 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(=O)OC4(C(C)=O)CCC3C1CCC2=CC(=O)CCC2=C1C(CC34C)c5ccc(N(C)C)cc5;
	InChI InChI=1S/C30H37NO4/c1-18(32)30(35-19(2)33)15-14-27-25-12-8-21-16-23(34)11-13-24(21)28(25)26(17-29(27,30)3)20-6-9-22(10-7-20)31(4)5/h6-7,9-10,16,25-27H,8,11-15,17H2,1-5H3/t25-,26+,27-,29-,30-/m0/s1 ; Key:OOLLAFOLCSJHRE-ZHAKMVSLSA-N ;
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Angol

ulipristal (tsz. ulipristals)

1 2 Forráshivatkozás-hiba: Érvénytelen <ref> címke; nincs megadva szöveg a(z) AHFS2017 nevű lábjegyzeteknek
↑ Prescription medicines: registration of new chemical entities in Australia, 2015. Therapeutic Goods Administration (TGA) , 2022. június 21.
↑ ellaOne 30 mg - Summary of Product Characteristics (SmPC). (emc) , 2021. július 1. [2023. december 8-i dátummal az eredetiből archiválva].
↑ Esmya 5 mg Tablets (ulipristal acetate) - Summary of Product Characteristics (SmPC). (emc) , 2021. február 17.
↑ Ella- ulipristal acetate tablet. DailyMed , 2023. november 1.
↑ Forráshivatkozás-hiba: Érvénytelen <ref> címke; nincs megadva szöveg a(z) ellaOne EPAR nevű lábjegyzeteknek