vortioxetine

vortioxetine

Clinical data
Pronunciation	/vɔːrtiˈɒksətiːn/ vor-tee-OK-sə-teen
Trade names	Trintellix, Brintellix, others
Other names	Lu AA21004, Vortioxetine hydrobromide (JAN JP), Vortioxetine hydrobromide (USAN US)
AHFS/Drugs.com	Monograph
MedlinePlus	a614003
License data	US DailyMed: Vortioxetine
Pregnancy category	AU: B3
Routes of administration	By mouth
Drug class	Serotonin modulator and stimulator (SMS)
ATC code	N06AX26 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) BR: Class C1 (Other controlled substances) CA: ℞-only UK: POM (Prescription only) US: ℞-only EU: Rx-only In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability	75% (peak at 7–11 hours)
Protein binding	98–99%
Metabolism	Liver, primarily CYP2D6-mediated oxidation
Elimination half-life	66 hours
Excretion	59% in urine, 26% in feces
Identifiers
IUPAC name 1-[2-(2,4-Dimethyl-phenylsulfanyl)phenyl]piperazine
CAS Number	508233-74-7 Y
PubChem CID	9966051
IUPHAR/BPS	7351
DrugBank	DB09068 Y
ChemSpider	8141643 Y
UNII	3O2K1S3WQV as salt: TKS641KOAY
KEGG	D10184 Y as salt: D10185 Y
ChEBI	CHEBI:76016 Y
ChEMBL	ChEMBL2204360 Y
Chemical and physical data
Formula	C18H22N2S
Molar mass	298.448 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(C=C(C)C=C1)=C1SC2=C(N3CCNCC3)C=CC=C2
InChI InChI=1S/C18H22N2S/c1-14-7-8-17(15(2)13-14)21-18-6-4-3-5-16(18)20-11-9-19-10-12-20/h3-8,13,19H,9-12H2,1-2H3 N Key:YQNWZWMKLDQSAC-UHFFFAOYSA-N N
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Angol

Főnév

vortioxetine (tsz. vortioxetines)

1. (gyógyszertan) vortioxetin

További információk

• vortioxetine - Szótár.net (en-hu)
• vortioxetine - Sztaki (en-hu)
• vortioxetine - Merriam–Webster
• vortioxetine - Cambridge
• vortioxetine - WordNet
• vortioxetine - Яндекс (en-ru)
• vortioxetine - Google (en-hu)
• vortioxetine - Wikidata
• vortioxetine - Wikipédia (angol)