aspirin

Acetylsalicylic acid

Clinical data
Pronunciation	/əˌsiːtəlˌsælɪˈsɪlɪk/
Trade names	Bayer Aspirin, others
Other names	2-acetoxybenzoic acid 2-(acetyloxy)benzoic acid o-acetylsalicylic acid acetylsalicylic acid acetyl salicylate salicylic acid acetate o-carboxyphenyl acetate monoacetic acid ester of salicylic acid
AHFS/Drugs.com	Monograph
MedlinePlus	a682878
License data	US DailyMed: Acetylsalicylic acid
Pregnancy category	AU: C
Routes of administration	Oral, rectal
Drug class	Nonsteroidal anti-inflammatory drug (NSAID)
ATC code	A01AD05 (WHO) B01AC06 (WHO), N02BA01 (WHO)
Legal status
Legal status	AU: OTC / Schedule 2, 4, 5, 6 CA: OTC UK: General sales list (GSL, OTC) US: OTC / Rx-only
Pharmacokinetic data
Bioavailability	80–100%
Protein binding	80–90%
Metabolism	Liver (CYP2C19 and possibly CYP3A), some is also hydrolysed to salicylate in the gut wall.
Elimination half-life	Dose-dependent; 2–3 h for low doses (100 mg or less), 15–30 h for larger doses.
Excretion	Urine (80–100%), sweat, saliva, feces
Identifiers
IUPAC name 2-acetyloxybenzoic acid
CAS Number	50-78-2 Y
PubChem CID	2244
IUPHAR/BPS	4139
DrugBank	DB00945 Y
ChemSpider	2157 Y
UNII	R16CO5Y76E
KEGG	D00109 Y C01405 Y
ChEBI	CHEBI:15365 Y
ChEMBL	ChEMBL25 Y
PDB ligand	AIN (PDBe, RCSB PDB)
Chemical and physical data
Formula	C9H8O4
Molar mass	180.159 g·mol−1
3D model (JSmol)	Interactive image
Density	1.40 g/cm3
Melting point	135 °C (275 °F)
Boiling point	140 °C (284 °F) (decomposes)
Solubility in water	3 g/L
SMILES O=C(C)Oc1ccccc1C(=O)O
InChI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) Y Key:BSYNRYMUTXBXSQ-UHFFFAOYSA-N Y
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Angol

Főnév

aspirin (tsz. aspirins)

1. (gyógyszertan) aszpirin

További információk

• aspirin - Szótár.net (en-hu)
• aspirin - Sztaki (en-hu)
• aspirin - Merriam–Webster
• aspirin - Cambridge
• aspirin - WordNet
• aspirin - Яндекс (en-ru)
• aspirin - Google (en-hu)
• aspirin - Wikidata
• aspirin - Wikipédia (angol)