colchicine

colchicine

Clinical data
Pronunciation	/ˈkɒltʃɪsiːn/ KOL-chiss-een
Trade names	Colcrys, Mitigare, others
AHFS/Drugs.com	Monograph
MedlinePlus	a682711
License data	US DailyMed: Colchicine
Pregnancy category	AU: D
Routes of administration	By mouth
ATC code	M04AC01 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) CA: ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability	45%
Protein binding	35-44%
Metabolism	Metabolism, partly by CYP3A4
Elimination half-life	26.6-31.2 hours
Excretion	Feces (65%)
Identifiers
IUPAC name N-[(7S)-1,2,3,10-Tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide
CAS Number	64-86-8 Y
PubChem CID	6167
IUPHAR/BPS	2367
DrugBank	DB01394 Y
ChemSpider	5933 Y
UNII	SML2Y3J35T
KEGG	D00570 Y
ChEBI	CHEBI:27882 Y
ChEMBL	ChEMBL107 Y
Chemical and physical data
Formula	C22H25NO6
Molar mass	399.443 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC
InChI InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1 Y Key:IAKHMKGGTNLKSZ-INIZCTEOSA-N Y
(verify)

Angol

Főnév

colchicine (tsz. colchicines)

1. (gyógyszertan) kolchicin

További információk

• colchicine - Szótár.net (en-hu)
• colchicine - Sztaki (en-hu)
• colchicine - Merriam–Webster
• colchicine - Cambridge
• colchicine - WordNet
• colchicine - Яндекс (en-ru)
• colchicine - Google (en-hu)
• colchicine - Wikidata
• colchicine - Wikipédia (angol)