octopamine

Octopamine

Clinical data
Trade names	Epirenor, Norden, Norfen
Other names	OCT, Norsympathol, Norsynephrine, para-Octopamine, beta-Hydroxytyramine, 4,β-dihydroxyphenethylamine, para-hydroxy-phenyl-ethanolamine, α-(Aminomethyl)-4 hydroxybenzenemethanol, 1-(p-Hydroxyphenyl)-2-aminoethanol
Routes of administration	Oral
ATC code	C01CA18 (WHO)
Physiological data
Source tissues	Invertebrate nervous systems; trace amine in vertebrates
Target tissues	System-wide in invertebrates
Receptors	TAAR1 (mammals) OctαR, OctβR, TyrR (invertebrates), Oct-TyrR
Agonists	Formamidines (amitraz (AMZ) and chlordimeform (CDM))
Antagonists	Epinastine
Precursor	Tyramine
Biosynthesis	Tyramine β-hydroxylase; dopamine β-hydroxylase
Metabolism	p-Hydroxymandelic acid;
Legal status
Legal status	US: Prohibited from use in food or supplements. Rx / Uncontrolled / Banned by World Anti-Doping Agency
Pharmacokinetic data
Bioavailability	99.42%
Metabolism	p-Hydroxymandelic acid;
Elimination half-life	15 minutes in insects. Between 76 and 175 minutes in humans
Excretion	Up to 93% of ingested octopamine is eliminated via the urinary route within 24 hours
Identifiers
IUPAC name (RS)-4-(2-amino-1-hydroxy-ethyl)phenol
CAS Number	104-14-3 Y
PubChem CID	4581
IUPHAR/BPS	2149
ChemSpider	4420 Y
UNII	14O50WS8JD
KEGG	C04227
ChEBI	CHEBI:17134 N
ChEMBL	ChEMBL53929 Y
Chemical and physical data
Formula	C8H11NO2
Molar mass	153.181 g·mol−1
3D model (JSmol)	Interactive image
SMILES OC(c1ccc(O)cc1)CN
InChI InChI=1S/C8H11NO2/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4,8,10-11H,5,9H2 Y Key:QHGUCRYDKWKLMG-UHFFFAOYSA-N Y
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Angol

Főnév

octopamine (tsz. octopamines)

1. (gyógyszertan) oktopamin

További információk

• octopamine - Szótár.net (en-hu)
• octopamine - Sztaki (en-hu)
• octopamine - Merriam–Webster
• octopamine - Cambridge
• octopamine - WordNet
• octopamine - Яндекс (en-ru)
• octopamine - Google (en-hu)
• octopamine - Wikidata
• octopamine - Wikipédia (angol)