serotonin

serotonin

Clinical data
Other names	5-HT, 5-Hydroxytryptamine, Enteramine, Thrombocytin, 3-(β-Aminoethyl)-5-hydroxyl solution , Thrombotonin
Physiological data
Source tissues	raphe nuclei, enterochromaffin cells
Target tissues	system-wide
Receptors	5-HT1, 5-HT2, 5-HT3, 5-HT4, 5-HT5, 5-HT6, 5-HT7
Agonists	Indirectly: SSRIs, MAOIs
Precursor	5-HTP
Biosynthesis	Aromatic L-amino acid decarboxylase
Metabolism	MAO
Identifiers
IUPAC name 3-(2-Aminoethyl)-1H-indol-5-ol
CAS Number	50-67-9
PubChem CID	5202
IUPHAR/BPS	5
ChemSpider	5013
KEGG	C00780
PDB ligand	SRO (PDBe, RCSB PDB)
Chemical and physical data
Molar mass	0 g·mol−1

serotonin

Ball-and-stick model of the serotonin molecule
Names
IUPAC name 5-Hydroxytryptamine
Preferred IUPAC name 3-(2-Aminoethyl)-1H-indol-5-ol
Other names 5-Hydroxytryptamine, 5-HT, Enteramine; Thrombocytin, 3-(β-Aminoethyl)-5-hydroxyindole, 3-(2-Aminoethyl)indol-5-ol, Thrombotonin
Identifiers
CAS Number	50-67-9 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:28790 Y
ChEMBL	ChEMBL39 Y
ChemSpider	5013 Y
IUPHAR/BPS	5
KEGG	C00780 Y
MeSH	Serotonin
PubChem CID	5202
UNII	333DO1RDJY Y
InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 Y Key: QZAYGJVTTNCVMB-UHFFFAOYSA-N Y InChI=1/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 Key: QZAYGJVTTNCVMB-UHFFFAOYAX
SMILES C1=CC2=C(C=C1O)C(=CN2)CCN
Properties
Chemical formula	C10H12N2O
Molar mass	176.215 g/mol
Appearance	White powder
Melting point	167.7 °C (333.9 °F; 440.8 K) 121–122 °C (ligroin)
Boiling point	416 ± 30 °C (at 760 Torr)
Solubility in water	slightly soluble
Acidity (pKa)	10.16 in water at 23.5 °C
Dipole moment	2.98 D
Hazards
Lethal dose or concentration (LD, LC):
LD50 (median dose)	750 mg/kg (subcutaneous, rat),
Safety data sheet (SDS)	External MSDS
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is YN ?) Infobox references

Angol

Főnév

serotonin (tsz. serotonins)

1. (gyógyszertan) szerotonin

További információk

• serotonin - Szótár.net (en-hu)
• serotonin - Sztaki (en-hu)
• serotonin - Merriam–Webster
• serotonin - Cambridge
• serotonin - WordNet
• serotonin - Яндекс (en-ru)
• serotonin - Google (en-hu)
• serotonin - Wikidata
• serotonin - Wikipédia (angol)