valacyclovir

valacyclovir

Clinical data
Trade names	Valtrex, Zelitrex, others
Other names	valacyclovir, valacyclovir hydrochloride (USAN US)
AHFS/Drugs.com	Monograph
MedlinePlus	a695010
License data	US DailyMed: Valacyclovir
Pregnancy category	AU: B3
Routes of administration	By mouth
Drug class	Antiviral
ATC code	J05AB11 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability	55%
Protein binding	13–18%
Metabolism	Liver (to aciclovir)
Elimination half-life	<30 minutes (valaciclovir); 2.5–3.6 hours (aciclovir)
Excretion	Kidney 40–50% (aciclovir), faecal 47% (aciclovir)
Identifiers
IUPAC name 2-[(2-Amino-6-oxo-1H-purin-9-yl)methoxy]ethyl (2S)-2-amino-3-methylbutanoate
CAS Number	124832-26-4 Y as HCl: 124832-27-5
PubChem CID	135398742 as HCl: 135398741
IUPHAR/BPS	4824
DrugBank	DB00577 Y as HCl: DBSALT000289
ChemSpider	54770 Y
UNII	MZ1IW7Q79D as HCl: G447S0T1VC
KEGG	D08664 Y as HCl: D00398
ChEBI	CHEBI:35854 Y as HCl: CHEBI:9919
ChEMBL	ChEMBL1349 Y as HCl: ChEMBL1201110
NIAID ChemDB	070982
Chemical and physical data
Formula	C13H20N6O4
Molar mass	324.341 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(OCCOCn1c2N\C(=N/C(=O)c2nc1)N)[C@@H](N)C(C)C
InChI InChI=1S/C13H20N6O4/c1-7(2)8(14)12(21)23-4-3-22-6-19-5-16-9-10(19)17-13(15)18-11(9)20/h5,7-8H,3-4,6,14H2,1-2H3,(H3,15,17,18,20)/t8-/m0/s1 Y Key:HDOVUKNUBWVHOX-QMMMGPOBSA-N Y
NY (what is this?)  (verify)

Angol

Főnév

valacyclovir (tsz. valacyclovirs)

1. (gyógyszertan) valaciklovir

További információk

• valacyclovir - Szótár.net (en-hu)
• valacyclovir - Sztaki (en-hu)
• valacyclovir - Merriam–Webster
• valacyclovir - Cambridge
• valacyclovir - WordNet
• valacyclovir - Яндекс (en-ru)
• valacyclovir - Google (en-hu)
• valacyclovir - Wikidata
• valacyclovir - Wikipédia (angol)